Reducing iron expression could more effectively treat brain tumoursRSS Feed

Iron could be instrumental in treating the brain injury seen in brain cancer, research has shown.

Brain cancer therapy could be more effective if the expression of an iron-storing protein is lessened, according to research published in journal Cancer Research.

According to study authors, this would increase the sensitivity of the cancer cells to drugs, potentially improving the effect of therapeutic drugs on brain cancer cells.

Currently, effective amounts of chemotherapy drugs are not reaching the malignant glioblastoma multiforme tumour. Increasing the dosage would cause damage and so elevating the sensitivity of the cells could be effective, authors explain.

James Connor, of Penn State College of Medicine, said: "About half of all brain tumors are resistant to chemotherapy and new therapeutic strategies are urgently needed to treat this cancer."

This follows the Food and Drug Administration's approval of a new device to treat patients with reoccurring brain tumours, according to oncology company Novocure.

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