Researchers have identified four different genes that increase the risk of an individual developing the brain injury seen in Alzheimer's disease.
A team from Mount Sinai School of Medicine analysed more than 11,000 people with the condition and almost the same number of older people who exhibited no signs of dementia.
It is hoped that the results, published in journal Nature Genetics, will help scientists predict which individuals will develop Alzheimer's disease.
Joseph Buxbaum of the institute elaborated: "Follow up studies of the genes identified, to determine how they affect brain biochemistry, are now possible in our samples, and this can help us understand how the genes contribute to Alzheimer's disease."
A study published in the Annals of Neurology has also given scientists more clues as to which patients will develop the neurodegenerative condition.
It was found that the amyloid plaques associated with Alzheimer's disease appear in the brain years before symptoms of the condition manifest themselves.
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Posted by Matthew Dixon
