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Chemical found to 'improve learning'

New findings about the process of learning could help patients with brain injury such as Alzheimer's disease.

Researchers from the University of Bristol have found a link between the neural triggers linked to learning and the state of the brain at the time.

Currently, the only treatment for Alzheimer's which has proved effective uses drugs that boost the amount of acetylcholine - a chemical essential for the acquisition of new memories.

Scientists found acetylcholine inhibits the activity of SK channels that would usually restrict the activity of NMDA receptors, which control the strength of connections between nerve cells in the brain.

Findings indicate that the SK channel barrier can be removed by the utilisation of acetylcholine, which would improve the brain's ability to learn information.

Lead researcher Dr Jack Mellor said that the findings would not revolutionise the treatment of Alzheimer's overnight.

"National and international funding bodies have recently made research into aging and dementia a top priority so we expect many more advances in our understanding of the mechanisms underlying learning and memory in both health and disease," he said.

This comes after scientists at Cambridge University found that the confusion seen in patients with dementia could be due to false memories rather than memory loss.

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Posted by Timothy Walters
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