Scientists in the US have isolated a new signalling pathway between brain tumour cells that could lead to treatment of one of the most malignant causes of acquired brain injury.
Glioblastoma multiforme (GBM) is deadly form of solid tumour cancer, which causes brain injury and death in patients, has so far defied all scientific progress.
Scientists from the University of California, San Diego (UCSD) School of Medicine have located a signalling pathway between GMB cells that could be blocked or disrupted, potentially slowing tumour growth.
"If we can inhibit or block this cellular communication, the tumour does not grow as quickly and may be more treatable," explained associated professor of medicine at the UCSD School of Medicine Frank Furnari.
He suggested that future treatments may focus on the diverse range of mutations that marks out GMBs as particularly deadly, as currently most treatments can only target a specific mutation.
According to Brain Tumour UK, a third of child cancer deaths stem from brain and central nervous system tumours.
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Posted by Matthew Heap
