Glycerol 'does not help' meningitis brain damage patientsRSS Feed

Glycerol has been found not to help meningitis patients who have suffered from brain injury.

Research published in the BMC Infectious Disease journal tested the effect of glycerol on infant rats and adult mice which had pneumococcal meningitis, with the animals being given ceftriaxone and glycerol or a placebo.

After being given the treatment, they were tested for brain damage, hearing loss and inflammatory parameters.

The results showed that the animals treated with glycerol and a placebo did not differ, neither clinically nor by histopathology.

According to the report: "While both groups showed equally high levels of matrix metalloproteinase-9 at 24 h after infection, a significant difference in favour of glycerol was observed at 40 h after infection."

The finding follows recent research from Rainer Scheid and D Yves von Cramon, published in the Deutsches Arzteblatt International journal, which stated that there is no link between physical and psychological functions and brain injury.

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